Paxton has a sore throat, so his mother has taken him to the doctor. His older sister, Paige, tags along just to make trouble. During Paxton’s exam, the siblings are horrified to learn that there are tiny creatures living in Paxton’s mouth—and ours too!
That’s when the doctor’s visit turns into an amazing scientific expedition into the small world of microorganisms. The doctor takes the Puzzle family to the lab where they meet Puzzleland’s renowned microbiologist and see some of these tiny creatures first hand. There, they discover a fascinating microscopic world and that the tiny living creatures in that world are just like everything else: some are good and some are bad.